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Product info: Other Anti-Depressant - Buspar
Buspar: BuSpar is used for the short-term relief of anxiety symptoms.

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Information for Patients

To assure safe and effective use of BuSpar, the following information and instructions should be given to patients:
Inform your physician about any medications, prescription or non-prescription, alcohol, or drugs that you are now taking or plan to take during your treatment with BuSpar.
Inform your physician if you are pregnant, or if you are planning to become pregnant, or if you become pregnant while you are taking BuSpar.
Inform your physician if you are breast-feeding an infant.
Until you experience how this medication affects you, do not drive a car or operate potentially dangerous machinery.
You should take BuSpar (buspirone hydrochloride) consistently, either always with or always without food.
During your treatment with BuSpar, avoid drinking large amounts of grapefruit juice.
Laboratory Tests

There are no specific laboratory tests recommended.
Drug Interactions
Psychotropic Agents

MAO inhibitors: It is recommended that BuSpar not be used concomitantly with MAO inhibitors (see WARNINGS).

Amitriptyline: After addition of buspirone to the amitriptyline dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) of amitriptyline or its metabolite nortriptyline were observed.

Diazepam: After addition of buspirone to the diazepam dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) were observed for diazepam, but increases of about 15% were seen for nordiazepam, and minor adverse clinical effects (dizziness, headache, and nausea) were observed.

Haloperidol: In a study in normal volunteers, concomitant administration of buspirone and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear.

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